High-resolution structural studies provided direct visualization of the transporters binding interactions with glutathione molecules, decoding the molecular basis for its specificity and kinetics
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Apoptosis detection on cells treated for 24 h and 48 h revealed that OA-NPs@OA induced apoptosis rates of 29.3% and 38.5% in HaCaT cells, respectively, both significantly higher than those of free OA (11.35% and 18.22%), indicating enhanced apoptotic induction capability of OA-NPs@OA (Fig